Flu or Influenza is caused by an Orthomyxovirus (a type of RNA virus) which is discovered by Andrew and smith. Most of us think that Common cold and flu are same but they are not. Common Cold is caused by Rhinovirus but its affect the respiratory Tract as Flu.
Hemagglutinin and Neuraminidase are the "Spike" of Virus.
-Hemagglutinin helps in attachment of virus on epithelial cells of respiratory cell
-Neuraminidase helps to facilitate the passage of viral genetic material host into epithelial cell
Pathogenesis :
The RNA virus enter into respiratory portal as the route of entry and then enter into host-susceptible where the host's immune response triggers to secret mucus. In simple words, virus attacks the epithelial cells of respiratory tract.
Conditions :
You may ask why flu most of time affected us during cold season? This is due to the characteristics of flu which only can activate and multiply in cold condition of body. Because of this, doctors are not advised us to take cold or chills water at all for few days.
Sometime flu may be appear in pale yellow colour which is due to the bacterial infection of respiratory tract. And bloody flu is caused by the continuous sneezing or coughing will leads to the breakdown of capillaries.
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